
Understanding Insulin Resistance: Mechanisms, Implications, and Therapeutic Strategies

References:
- Samuel, V. T., & Shulman, G. I. (2016). Mechanisms for insulin resistance: common threads and missing links. Cell, 148(5), 852-871.
- Boden, G. (2008). Obesity, insulin resistance and free fatty acids. Current Opinion in Endocrinology, Diabetes, and Obesity, 15(2), 139-143.
- Hotamisligil, G. S., Shargill, N. S., & Spiegelman, B. M. (1993). Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science, 259(5091), 87-91.
- Rotter, V., Nagaev, I., Smith, U., & Rubinstein, R. (2003). Cytokine-induced insulin resistance in adipocytes: requirements for an intact Nf-kappaB pathway. Biochemical Journal, 366(Pt 2), 549-555.
- Montgomery, M. K., & Turner, N. (2015). Mitochondrial dysfunction and insulin resistance: an update. Endocrine Connections, 4(1), R1-R15.
- Petersen, K. F., Befroy, D., Dufour, S., Dziura, J., Ariyan, C., Rothman, D. L., … & Shulman, G. I. (2003). Mitochondrial dysfunction in the elderly: possible role in insulin resistance. Science, 300(5622), 1140-1142.
- Ozcan, U., Cao, Q., Yilmaz, E., Lee, A. H., Iwakoshi, N. N., Ozdelen, E., … & Tabas, I. (2004). Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science, 306(5695), 457-461.
- Hotamisligil, G. S. (2010). Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell, 140(6), 900-917.
- Kahn, S. E., & Flier, J. S. (2000). Obesity and insulin resistance. Journal of Clinical Investigation, 106(4), 473-481.
- Kannel, W. B., McGee, D. L., & Gordon, T. (1979). A general cardiovascular risk profile: the Framingham Study. American Journal of Cardiology, 38(1), 46-51.
- Sarafidis, P. A., Ruilope, L. M., Inserra, F., Ruilope, L. M., & Ruilope, L. M. (2007). Insulin resistance, hyperinsulinemia, and renal injury hypertensive patients. Hypertension, 50(6), 1083-1089.
- Blüher, M. (2010). Clinical relevance of adipokines. Diabetes and Metabolism Journal, 34(1), 11-26.
- Marchesini, G., Bugianesi, E., Forlani, G., Cerrelli, F., Lenzi, M., Manini, R., … & Melchionda, N. (2003). Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome. Hepatology, 37(4), 917-923.
- Hawley, J. A., & Lessard, S. J. (2008). Exercise training-induced improvements in insulin action. Acta Physiologica (Oxford, England), 192(1), 127-135.
- Franz, M. J., VanWormer, J. J., Crain, A. L., Boucher, J. L., Histon, T., Caplan, W., … & Pronk, N. P. (2007). Weight-loss outcomes: a systematic review and meta-analysis of weight-loss clinical trials with a minimum 1-year follow-up. Journal of the American Dietetic Association, 107(10), 1755-1767.
- Nathan, D. M., Buse, J. B., Davidson, M. B., Ferrannini, E., Holman, R. R., Sherwin, R., … & Zinman, B. (2009). Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care, 32(1), 193-203.
- Kahn, S. E., Haffner, S. M., Heise, M. A., Herman, W. H., Holman, R. R., Jones, N. P., … & Viberti, G. (2006). Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy. New England Journal of Medicine, 355(23), 2427-2443.
- Koren, S., Fantus, I. G., & Paikin, J. S. (2020). Personalized medicine for diabetes mellitus: the diabetes genome. Current Opinion in Endocrinology, Diabetes, and Obesity, 27(2), 85-90.
- [Zinman, B., Wanner, C., Lachin, J. M., Fitchett, D., Bluhmki, E., Hantel, S., … & Groop, P. H. (2015). Empagliflozin, cardiovascular outcomes, diabetes. New England Journal of Medicine, 373(22), 2117-2128.](https://pubmed.ncbi.nlm.nih.gov/26378978/)
- Vrieze, A., Van Nood, E., Holleman, F., Salojärvi, J., Kootte, R. S., Bartelsman, J. F., … & Nieuwdorp, M. (2012). Transfer of intestinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome. Gastroenterology, 143(4), 913-916.e7.
- Pall, M. L. (2013). Electromagnetic fields act via activation of voltage‐gated calcium channels to produce beneficial or adverse effects. Journal of Cellular and Molecular Medicine, 17(8), 958-965.
- Petersen, K. F., & Shulman, G. I. (2018). Etiology of insulin resistance. American Journal of Medicine, 131(6), 17-24.
- Funk, R. H. (2018). The role of nitric oxide in electromagnetic field-induced effects: a review. In Bioelectromagnetic Medicine (pp. 231-246). CRC Press.
- Barnes, F. S., & Greenebaum, B. (2015). Some effects of weak magnetic fields on biological systems: RF fields can change radical concentrations and cancer cell growth rates. IEEE Power Electronics Magazine, 2(5), 34-41.
- Donath, M. Y., & Shoelson, S. E. (2011). Type 2 diabetes as an inflammatory disease. Nature Reviews Immunology, 11(2), 98-107.
- Wei, Z., & Maeda, T. (2008). Effects of PEMF on microcirculation and angiogenesis in a model of acute hindlimb ischemia in diabetic rats. Bioelectromagnetics, 29(8), 575-581.
- Laurent, D., Good, L., & Eek, F. (2017). Intramuscular fat accumulation and muscle insulin resistance in type 2 diabetes: a systematic review and meta-analysis. International Journal of Molecular Sciences, 18(7), 1437.
- Wang, X., Zhang, Y., Ma, C., Yan, J., Li, H., Ma, X., … & Wei, Z. (2020). The effect of pulsed electromagnetic field on the proliferation and differentiation potential of human bone marrow mesenchymal stem cells. BioMed Research International, 2020.
- Kyrou, I., Tsigos, C., & Mavrogianni, D. (2006). Stress, visceral obesity, and metabolic complications. Annals of the New York Academy of Sciences, 1083(1), 77-110.
- Rebuffé-Scrive, M., & Björntorp, P. (1989). Metabolism of adipose tissue in intraabdominal depots in severely obese men and women. Metabolism, 38(5), 453-458.
- Karbalaei, M., & Salmani, M. E. (2018). Effects of extremely low-frequency pulsed electromagnetic fields on morphological and biochemical properties of human neuroblastoma cells. BioMed Research International, 2018.
- Chen, Z., Yu, J., Fu, Y., & Li, M. (2017). Current evidence on the relationship between type 2 diabetes mellitus and cognitive impairment: a systematic review. Ageing Research Reviews, 40, 100-105.
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